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Physical & Chemical properties

Dissociation constant

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Administrative data

Endpoint:
dissociation constant
Type of information:
not specified
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Valproic acid
Year:
2017
Bibliographic source:
ChemIDPlus Advanced

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No data on method available

Test material

Constituent 1
Reference substance name:
Valproic acid
IUPAC Name:
Valproic acid
Constituent 2
Chemical structure
Reference substance name:
2-propylvaleric acid
EC Number:
202-777-3
EC Name:
2-propylvaleric acid
Cas Number:
99-66-1
Molecular formula:
C8H16O2
IUPAC Name:
2-propylpentanoic acid

Results and discussion

Dissociating properties:
yes
Dissociation constant
No.:
#1
pKa:
4.6
Remarks on result:
other: no information on temperature value

Applicant's summary and conclusion

Conclusions:
Valproic acid has a dissociation constant pKa=4.6