Registration Dossier
Registration Dossier
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EC number: 202-777-3 | CAS number: 99-66-1
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- Valproic acid
- IUPAC Name:
- Valproic acid
- Details on test material:
- - Supplied by Parke-Davis Pharmaceutical Research Division
- The percentages of active component (valproic acid) were determined by a gas-chromatographic assay for purposes of dose calculation.
Constituent 1
Results and discussion
Boiling point
- Key result
- Boiling pt.:
- 226.5 °C
- Atm. press.:
- 99.67 kPa
Applicant's summary and conclusion
- Conclusions:
- Valproic acid has a boiling point of 226.5°C (temperature: 499.7 K, atmospheric pressure: 99.67 kPa)
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