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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
10.2 mg/L

Additional information

Read across on Sodium Valproate

Method: OECD Test Guideline 210

Species: Danio rerio (zebra fish) 

Exposure duration: 30 d 

Hatching Success: NOEC ≥ 10.2 mg test item/L (mean measured concentrations)

Mortality/Survival at the End of the Test (30 days post-hatch): NOEC ≥ 10.2 mg test item/L (mean measured concentrations), LOEC > 10.2 mg test item/L (mean measured concentrations), LC10/20/50 = n.d

Body Length: NOEC ≥ 10.2 mg test item/L (mean measured concentrations), LOEC > 10.2 mg test item/L (mean measured concentrations)

Body Weight (wet): NOEC ≥ 10.2 mg test item/L (mean measured concentrations), LOEC > 10.2 mg test item/L (mean measured concentrations)

Body Weight (dry): NOEC ≥ 10.2 mg test item/L (mean measured concentrations), LOEC > 10.2 mg test item/L (mean measured concentrations)

10.2 mg/L was the highest tested dose.

Based on the read across on sodium valproate, valproic acid is expected to have a NOEC ≥ 10.2 mg test item/L and a LOEC : > 10.2 mg test item/L.