Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 270-128-1 | CAS number: 68411-46-1
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
For the registered substance is an OECD 211 study availableThe EC10 (21d) reproduction was determined to be 1.69mg/L (loading rate/WAF) according to OECD 211.
An further supporting study according to OECD 211 for a structurally very similar substance: Reaction products of diphenylamine (CAS:636878-20-3) with nonene, branched is available. The EC10 (21d) reproduction was determined to be >4.12mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1.69 mg/L
Additional information
In a chronic toxicity test on Daphnia magna reproduction according to OECD 211 the UVCB substance was investigated at saturation concentration (BASF 2016). As the test substance is a UVCB substance which is sparingly soluble in water, the test solution was prepared following general guidance provided in OECD 23 in order to generate a water accommodated fraction of the test substance in test medium (undiluted filtrate up to a loading rate of 10 mg/L). A clear relationship between loading rates of the WAFs and reproduction of the daphnids was determined in this test. However, the EC10 reproduction after 21 days was determined to be > 1mg/L.
impurity Diphenylamine:
The EU risk assessment report for Diphenylamine reports for a chronic invertebrate test with Daphnia magna (OECD 202, part II) after 21d a NOEC of 0.16 mg/L for reproduction.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
