Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

For the registered substance  is an OECD 211 study availableThe EC10 (21d) reproduction was determined to be 1.69mg/L (loading rate/WAF) according to OECD 211.

An further supporting study according to OECD 211 for a structurally very similar substance: Reaction products of diphenylamine (CAS:636878-20-3) with nonene, branched is available. The EC10 (21d) reproduction was determined to be >4.12mg/L.


Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1.69 mg/L

Additional information

In a chronic toxicity test on Daphnia magna reproduction according to OECD 211 the UVCB substance was investigated at saturation concentration (BASF 2016). As the test substance is a UVCB substance which is sparingly soluble in water, the test solution was prepared following general guidance provided in OECD 23 in order to generate a water accommodated fraction of the test substance in test medium (undiluted filtrate up to a loading rate of 10 mg/L). A clear relationship between loading rates of the WAFs and reproduction of the daphnids was determined in this test. However, the EC10 reproduction after 21 days was determined to be > 1mg/L.


impurity Diphenylamine:

The EU risk assessment report for Diphenylamine reports for a chronic invertebrate test with Daphnia magna (OECD 202, part II) after 21d a NOEC of 0.16 mg/L for reproduction.