Nickel difluoride

Long-term toxicity to fish

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:

0.066 mg/L

EC10, LC10 or NOEC for marine water fish:

5.9 mg/L

Additional information

Fresh Water ion Nickel

High quality NOEC/L(E)C10 values for chronic toxicity to freshwater fish are based on three fish species, Pimephales promelas, Oncorhynchus mykiss, and Brachydanio rerio. The NOEC/L(E)C10 values for fish range from 40 μg/l for Brachydanio rerio (Dave & Xiu, 1991) to 1548 μg/l for the Oncorhynchus mykiss (Deleebeeck et al., 2005a). 

Fresh Water ion Fluoride

Among valid data in the literature, Shi et al. (2009) found the lowest NOEC in fish in 90 days in Acipenser baerii (sturgeon): 4 mg F-/L (measured).

CONCLUSION NOEC 40ug/L Ni = NOEC 66ug/l NiF2

Marine Water ion Nickel

Chronic toxicity values are reported for two marine fish species. EC10 values range from 3.6 mg Ni/L for growth of the topsmelt, Atherinops affinis (Hunt et al., 2002), to 20.8 mg Ni/L for growth of the sheepshead minnow, Cyprinodon variegatus(Golder et al., 2007)

Marine Water ion Fluoride

Mugil cephalus: NOEC 113d on juvenile development = 5.5 mg/L.

Concer threshold for ion fluoride is much above the limit for Nickel, which is the quantity to be considered

CONCLUSION NOEC 3.6 mg/L Ni = NOEC 5.9 mg/l NiF2

FOR AN EXTENSIVE DISCUSSION, REFER TO THE NICKEL SULFATE DOSSIER WHICH IS BASED ON THE CONCLUSIONS EXPLAINED IN THE 2008/2009 EUROPEAN UNION EXISITING SUBSTANCE RISK ASSESSMENT OF NICKEL (EU RAR) (EEC 793/93)