Registration Dossier
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EC number: 233-071-3 | CAS number: 10028-18-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater fish:
- 0.066 mg/L
- EC10, LC10 or NOEC for marine water fish:
- 5.9 mg/L
Additional information
Fresh Water ion Nickel
High quality NOEC/L(E)C10 values for chronic toxicity to freshwater fish are based on three fish species, Pimephales promelas, Oncorhynchus mykiss, and Brachydanio rerio. The NOEC/L(E)C10 values for fish range from 40 μg/l for Brachydanio rerio (Dave & Xiu, 1991) to 1548 μg/l for the Oncorhynchus mykiss (Deleebeeck et al., 2005a).
Fresh Water ion Fluoride
Among valid data in the literature, Shi et al. (2009) found the lowest NOEC in fish in 90 days in Acipenser baerii (sturgeon): 4 mg F-/L (measured).
CONCLUSION NOEC 40ug/L Ni = NOEC 66ug/l NiF2
Marine Water ion Nickel
Chronic toxicity values are reported for two marine fish species. EC10 values range from 3.6 mg Ni/L for growth of the topsmelt, Atherinops affinis (Hunt et al., 2002), to 20.8 mg Ni/L for growth of the sheepshead minnow, Cyprinodon variegatus(Golder et al., 2007)
Marine Water ion Fluoride
Mugil cephalus: NOEC 113d on juvenile development = 5.5 mg/L.
Concer threshold for ion fluoride is much above the limit for Nickel, which is the quantity to be considered
CONCLUSION NOEC 3.6 mg/L Ni = NOEC 5.9 mg/l NiF2
FOR AN EXTENSIVE DISCUSSION, REFER TO THE NICKEL SULFATE DOSSIER WHICH IS BASED ON THE CONCLUSIONS EXPLAINED IN THE 2008/2009 EUROPEAN UNION EXISITING SUBSTANCE RISK ASSESSMENT OF NICKEL (EU RAR) (EEC 793/93)
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