Registration Dossier
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EC number: 233-071-3 | CAS number: 10028-18-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50/LC50 for freshwater invertebrates:
- 0.021 mg/L
- EC50/LC50 for marine water invertebrates:
- 0.38 mg/L
Additional information
Freshwater (Nickel):
From the database of acute toxicity to freshwater invertebrates, there are 30 high quality studies which predominantly report the 48h LC50 as the endpoint. Twenty-four species are represented in these studies, dominated by Daphnia magna and Ceriodaphnia dubia. The 48h LC50s values range from 0.013 mg Ni/L (Ceriodaphnia dubia; Schubauer-Berigan et al., 1993) to 4970 mg Ni/L (Daphnia magna; Chapman and Recht, 1980).
Fresh water (Fluoride)
The lowest measured value for fluoride action is 14.6mg/L active on an amphipod Hylella azteca. This value is much hihjer than the recorded value for dissolved Ni. Fluoride contribution to NiF2 toxicity is negligible
CONCLUSION LC50 0.013 mg/L Ni = LC50 0.021 mg/L NiF2
Marine water (Nickel):
From the database of acute toxicity to marine invertebrates, there are 16 high quality studies which report predominantly 48h LC50 and 48h EC50 as the endpoint. Twenty species are represented in these studies. The 48h LC50s values range from 0.23 mg/L (Haliotis refescens; Hunt et al., 2002b) to 415 mg/L (Penaeus duorarum; Bentley et al., 1975b). The 48h EC50 values range from 0.35 mg/L (Crassostrea gigas; Martin et al., 1981a) to 4.66 mg/L (Artemia salina; Kissa et al., 1984).
Marine Water (Fluoride)
The lowest measured value for fluoride action is 10.5mg/L active in the arthropod Mysidopsis bahia. This value is much hihjer than the recorded value for dissolved Ni. Fluoride contribution to NiF2 toxicity is negligible
CONCLUSION LC50 0.23 mg/L Ni = LC50 0.38 mg/L NiF2
FOR AN EXTENSIVE DISCUSSION, REFER TO THE NICKEL SULFATE DOSSIER WHICH IS BASED ON THE CONCLUSIONS EXPLAINED IN THE 2008/2009 EUROPEAN UNION EXISITING SUBSTANCE RISK ASSESSMENT OF NICKEL (EU RAR) (EEC 793/93)
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