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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Environmental fate & pathways

Adsorption / desorption

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adsorption / desorption: screening
Type of information:
Adequacy of study:
supporting study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
See attached QMRF/QPRF
Principles of method if other than guideline:
The method has been developed specifically for organosilicon compounds. It is a linear regression based model. The descriptors are the log Kow and an indicator variable for the presence of an amine. See QMRF and QPRF for further details.
Sample No.:
log Koc
-0.6 dimensionless
20 °C
Remarks on result:
other: Predicted for the silanol hydrolysis product 3 -aminopropylsilanetriol
A predicted log Koc value of -0.6 at 20°C and pH 7 was determined for the silanol hydrolysis product of the submission substance using a relevant estimation method. The result is considered to be reliable.
adsorption / desorption: screening
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter

Description of key information


log Koc [3-(trimethoxysilyl)propyl isocyanate]: not relevant due to very rapid hydrolysis in contact with water

log Koc [3-(trimethoxysilyl)propylamine: not relevant due to rapid hydrolysis in contact with water

log Koc [3-aminopropylsilanetriol]: -0.6 at 20°C and pH 7 (QSAR)

Key value for chemical safety assessment

Additional information

3-(Trimethoxysilyl)propyl isocyanate hydrolyses very rapidly (half-life <5 min at pH 7 for the hydrolysis of the isocyanate group) to form 3-(trimethoxysilyl)propylamine (intermediate hydrolysis product) and carbon dioxide. The intermediate hydrolysis product is expected to hydrolyse rapidly (2.6 hours at pH 7) to the final hydrolysis product 3-aminopropylsilanetriol and methanol. In view of these hydrolysis rates, risk assessment for the submission substance is carried out for the silanol hydrolysis product 3-aminopropylsilanetriol and methanol.

The log Koc of the silanol hydrolysis product, 3-aminopropylsilanetriol has been predicted using a validated QSAR estimation method to be -0.6 at 20°C and pH 7.