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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

No reliable acute toxicity data on fish are available for synthetic rutile. A read-across approach between synthetic rutile and TiO2 is used.  All reliable acute toxicity data to fish for TiO2 resulted in unbounded LC50 values ranging from >1 to >10000 mg TiO2/L, as observed for 4 different fish species in both freshwater and salt water. These reliable results cover a range of TiO2 products with varying particle size (from nano-particles to bulk powders).  All these results are taken together in a weight of evidence approach, and it is concluded that TiO2 is not acute toxic to fish at >1000 mg TiO2/L and at >10000 mg TiO2/L in freshwater and marine water, respectively.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Marine water fish

Marine water fish
Effect concentration:
10 000 mg/L

Additional information