Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 225-218-5 | CAS number: 4724-48-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
2 studies available (2002 and 2009)showing a readily biodegradation between 75.6% and 88% after 28 days.
1 study available (2012) showing a inherent biodegradation at 65% after 28 days
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Ready biodegradation
A study was performed to assess the ready biodegradability of the test item in an aerobic aqueous medium. The method was designed to be compatible with the OECD Guidelines for Testing of Chemicals (1992) No 301B, "CO2 evolution Test”
The test item, at a concentration of 12.4 mg C/L, was exposed to sewage treatment micro-organisms with mineral medium in open culture vessels (aerated) in the dark at ambiant temperatures for 28 days.
The degradation of the test item was assessed by the determination of the CO2 evolution. Control solutions with inoculum and the reference item, (sodium acetate trihydrate), together with a toxicity control were used for validation purposes.
The test item attained 88% degradation after 28 days and is considered to be readily biodegradable under the strict terms and conditions of OECD Guideline No 301B.
A study was performed to assess the ready biodegradability of the test item in an aerobic aqueous medium. The method was designed to be compatible with the OECD Guidelines for Testing of Chemicals (1992) No 301B, "CO2 evolution Test”
The test item, at a concentration of 12.7 mg TOC/L, was exposed to sewage treatment micro-organisms with mineral medium in open culture vessels (aerated) in the dark at ambiant temperatures for 28 days.
The degradation of the test item was assessed by the determination of the CO2 evolution. Control solutions with inoculum and the reference item, (sodium acetate trihydrate), together with a toxicity control were used for validation purposes.
The test item attained 75.6% degradation after 28 days and is considered to be readily biodegradable under the strict terms and conditions of OECD Guideline No 301B.
Inherent biodegradation
In a study (2012), the inherent biodegradability of Octylphosphonic Acid (OPA) (initial concentration: 202.1 mg/L), was tested in a Zahn-Wellens test during 28 days, according to OECD guideline for Testing of Chemicals n°302B (1992).
Inoculum used in the study was 300 mg/L of a sludge from a sewage treatment plant, (predominantly domestic sewage).
The percentage of biodegradation was estimated by following the DOC removal.
-OPA did not adsorb on activated sludge.
-OPA was not inhibitory to activated sludge at the tested concentration of 202.1 mg/L because degradation was > 35% within 14 days.
The corresponding percentage of biodegradation obtained was 65% of DOC removal after 28 days.
Under the test conditions, OPA is considered as inherent primary biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.