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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: quoted from Atochem 1989, original source not available

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Toxicology Data Summary Sheet
Author:
Atochem North America
Year:
1989
Reference Type:
publication
Title:
Structure Chimique et Activite Pharmacologique de Sels D'amines Tertiaire
Author:
Hazard, R., Cheymal, J., Chabrier. P. and Giudicelli, R.
Year:
1957
Bibliographic source:
Arch. Int. Pharmacodyn. 112 (1957) 36-49

Materials and methods

Test guideline
Guideline:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
2-dimethylaminoethanol
EC Number:
203-542-8
EC Name:
2-dimethylaminoethanol
Cas Number:
108-01-0
Molecular formula:
C4H11NO
IUPAC Name:
2-(dimethylamino)ethanol

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
no data

Administration / exposure

Route of administration:
intravenous
Details on exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 020 mg/kg bw

Applicant's summary and conclusion

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