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EC number: 269-798-8 | CAS number: 68333-89-1 The non-volatile, high-boiling residue from the distillation of products from cumene-phenol process. It consists predominantly of substituted phenyl groups crosslinked by carbon-oxygen bonds and phenylaliphatic bonds.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Experimental results on the acute toxicity of High-Boiler to fish are not available. Therefore, the results of acetophenone and phenol were taken into account for assessment.
Based on the available results of short-term toxicity tests with fish, the most sensitive endpoint was a 96 h LC50 of 8.9 mg/L, based on measured phenol concentrations, obtained in a study conducted under flow-through conditions with the cold water fish rainbow trout O. mykiss (96 h LC50 of acetophenone: 162 mg/L measured).
The acute toxicity of Z-Oil towards Daphnia magna was investigated in a study conducted according to OECD Guideline 202 and EU Method C.2. Daphnids were exposed to Z-Oil for 48 h at nominal concentrations ranging from 5 to 100 mg test item/L under static conditions. As the test item is poorly water-soluble, the aqueous extracts (WAFs) of the test substance were used in the test. The actual test concentration was checked by IR-spectroscopy. As the test item proved to be stable in the aqueous phase (>=80% recovery after 48 h), the test results were based on nominal concentrations. The 48 h NOEC, LOEC, and EL50 were determined to be 40, 80, 76.5 mg/L (nominal), respectively.
In a study conducted according to OECD Guideline 201 and EU Method C.3, cultures of Desmodesmus subspicatus were exposed to WAFs of Z-Oil for 72 h under static conditions. The actual test concentration was checked by IR-spectroscopy. As the test item proved to be stable in the aqueous phase (>=80% recovery after 72 h), the test results were based on nominal concentrations. The 72 h NOEC, LOEC, and EC50 based on growth rate were determined to be 80, 100, 96.4 mg/L (nominal), respectively. The corresponding values (72 h NOEC, LOEC, and EC50) based on yield were 80, 100, and 88.4 mg/L (nominal).
Experimental results on the long-term toxicity of High-Boiler to fish and aquatic invertebrates are not available. In Annex IX of Regulation (EC) No 1907/2006, it is laid down that chronic toxicity tests with fish and aquatic invertebrates shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on fish and aquatic invertebrates. The chemical safety assessment of High-Boiler reveals that it does not fulfil the criteria of a PBT or vPvB substance. From the available experimental study results on the UVCB itself as well as on main constituents there are no indications that the substance may be severely hazardous to aquatic organisms. According to reliable study results, High-Boiler is considered to be inherently biodegradable in the environment and the bioaccumulation potential is regarded to be insignificant. Therefore, with respect to animal welfare, the performance of chronic studies with fish and aquatic invertebrates is assumed to be not justifiable.
In a study conducted according to OECD Guideline 209 and EU Method C.11 the 3 h NOEC based on respiration inhibtion of the test item was determined as 100 mg/L (nominal).
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that toxicity tests in sediment organisms shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on sediment organisms. The chemical safety assessment of High-Boiler reveals that it does not fulfil the criteria of a PBT or vPvB substance. From the available experimental study results on the UVCB itself as well as on main constituents there are no indications that the substance may be severely hazardous to sediment organisms. According to reliable study results, high-boiler is considered to be inherently biodegradable in the environment and the bioaccumulation potential is regarded to be insignificant. Therefore, with respect to animal welfare, the performance of a toxicity test with sediment organisms is assumed to be not justifiable.
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