Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 269-798-8 | CAS number: 68333-89-1 The non-volatile, high-boiling residue from the distillation of products from cumene-phenol process. It consists predominantly of substituted phenyl groups crosslinked by carbon-oxygen bonds and phenylaliphatic bonds.
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the available results, the most sensitive endpoint was a 96 h LC50 of 8.9 mg phenol/L (measured) obtained in a study conducted under flow-through conditions with the cold water fish rainbow trout O. mykiss.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 8.9 mg/L
Additional information
Experimental results on the acute toxicity of High-Boiler to fish are not available. Therefore, the results of acetophenone and phenol were taken into account.
Based on the available results of short-term toxicity tests with fish, the most sensitive endpoint was a 96 h LC50 of 8.9 mg/L, based on measured phenol concentrations, obtained in a study conducted under flow-through conditions with the cold water fish rainbow trout O. mykiss. Several valid studies dealing with the acute toxicity of acetophenone towards fish are available. In studies conducted comparable to OECD Guideline and National Standard Methods, acetophenone shows a low toxicity towards Pimephales promelas: 96 h LC50=162 mg/L measured.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
