Registration Dossier

Administrative data

Description of key information

Full details of these endpoints are provided in the IUCLID dossier and they are considered reliable. The substance is considered "Harmful if swallowed" (Acute tox 4).
Results for the substance decyldimethylamine are presented below:
Under the conditions of the key study, the acute oral median lethal dosage (LD50) of the test material was greater than 2000 mg/kg. Accordingly, the substance was assigned to the class" low oral toxicity"

Key value for chemical safety assessment

Additional information

According to the key study, the acute oral median lethal dosage (LD50) of the test material was greater than 2000 mg/kg. Accordingly, the substance was assigned to the class" low oral toxicity".

According to the supporting study, the acute oral toxicity was determined in the Sprague-Dawley strain rat. The test method used was based on that descibed in the OECD 401 as Method B1. Initially, range-finding studies were performed to establish dosing regimes. Based on the results of these preliminary studies either a single group of ten animals (5 males and 5 females) was treated at a dose level of 200, 2000 or 5000 mg/kg bodyweight, or group of ten animals were treated with a range of logarithmically spaced dose levels.

No symbol or risk phrase are required according to EEC labelling regulations.

Justification for classification or non-classification