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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Toxicological information


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Administrative data

Description of key information

No neurotoxic effects were observed in the 14 week studies in rat and mouse (NIH, 2001).

Key value for chemical safety assessment

Additional information

Rats and mice exposed to DCDPS were subject functional observation screening battery of tests (NIH, 2001). This battery included tests to assess several aspects of neurologic function including autonomic, convulsive, excitability, neuromuscular, sensorimotor, and general motor activity domains. No significant signs for neurotoxicity were observable in the 14 week studies of NIH (2001) up to dose levels of 480 mg/kg bw/day in mouse and 200 mg/kg bw/day in rat.

Justification for classification or non-classification

The available observations give no evidence for significant neurotoxic effects. No effect level is derived.