Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1970 or earlier
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary source available, study report lacking.

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1970
Reference Type:
other company data
Title:
Unnamed
Year:
1991
Report date:
1991

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The test was performed in 1970, when no OECD, EU or EPA guideline was available.
GLP compliance:
no
Test type:
standard acute method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis(4-chlorophenyl) sulphone
EC Number:
201-247-9
EC Name:
Bis(4-chlorophenyl) sulphone
Cas Number:
80-07-9
Molecular formula:
C12H8Cl2O2S
IUPAC Name:
1-chloro-4-(4-chlorobenzenesulfonyl)benzene

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
no data

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Details on dermal exposure:
no data
Duration of exposure:
24 h
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Details on study design:
no data
Statistics:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 10 000 mg/kg bw
Based on:
test mat.
Mortality:
no data
Clinical signs:
other: no lesions observed on post mortem
Gross pathology:
no data
Other findings:
no data

Applicant's summary and conclusion

Conclusions:
The acute dermal toxicity value for DCDPS is reported >10 g/kg.
Executive summary:

The acute dermal LD50 in the rat is above 10000 mg/kg bw. No lesions occurred.