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EC number: 203-404-7 | CAS number: 106-50-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Phototransformation in water
Administrative data
- Endpoint:
- phototransformation in water
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- This GLP study generally follows the guideline. There are several deviations in the preparation and aging of the synthetic humic water, including no information on the measurement of DOC and the pre-aging time was seven days not three. These guideline differences and potential impacts were not discussed.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
- Study type:
- indirect photolysis
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EPA OTS 795.70 (Indirect Photolysis Screening Test: Sunlight Photolysis in Waters Containing Dissolved Humic Substances)
- Deviations:
- yes
- Remarks:
- The study generally follows the guideline. There are several deviations in the preparation synthetic humic water. These guideline differences and potential impacts were not discussed.
- GLP compliance:
- yes
Test material
- Details on test material:
- - Purity: 99.72%
Constituent 1
Study design
- Radiolabelling:
- not specified
- Analytical method:
- high-performance liquid chromatography
- Light source:
- sunlight
- Details on light source:
- Location: roof, 38ºN, facing south and angled at ~30º to the horizon
Time of year/month: summer/August
Other: Skies were clear during the whole exposure
Sensitiser (for indirect photolysis)
- Type of sensitiser:
- other: humic acid
- Details on sensitiser:
- synthetic humic water, pH 7
- Concentration of sensitiser:
- other: Absorbance (1cm cell @ 290 nm) = 0.1
- Dark controls:
- yes
- Remarks:
- (No significant losses were observed with the dark controls.)
Results and discussion
- Preliminary study:
- Loss of the test substance was 1.6 times faster in synthetic humic water (SHW) than distilled water and the half life in SHW was less than an hour. Therefore, according to the guideline, a definitive study was not necessary.
- Quantum yield (for direct photolysis):
- 0.02
- Rate constant (for indirect photolysis):
- 2.2 other: d-1
Dissipation half-life of parent compoundopen allclose all
- DT50:
- 0.12 d
- Test condition:
- Overall photolysis half-life. These results demonstrate that the substance is readily degraded by sunlight.
- DT50:
- 0.32 d
- Test condition:
- Indirect photolysis half-life
- Transformation products:
- not measured
Any other information on results incl. tables
Distilled Water (DW) and Synthetic Humic Water (SHW) Screening Study Results
Water Type |
Light Conditions |
Sample |
Time (PDT) |
Peak Height (mm), Injection #1 |
Peak Height (mm), Injection #2 |
Average Height, C (mm) |
ln(C0/Ct) |
Test Substance (µM) |
Test Substance % Reacted |
DW |
Start (Time 0) |
A |
11:20 |
43.2 |
43.9 |
44 |
0 |
10.5 |
0 |
DW |
Start (Time 0) |
B |
11:20 |
44.8 |
44.2 |
||||
DW |
Dark |
A |
12:00 |
44.4 |
45.2 |
45.3 |
-0.029 |
10.8 |
-3 |
DW |
Dark |
B |
12:00 |
45.3 |
46.1 |
||||
DW |
Light |
A |
12:00 |
22.2 |
22.2 |
22 |
0.693 |
5.2 |
50 |
DW |
Light |
B |
12:00 |
22.1 |
21.3 |
||||
SHW |
Start (Time 0) |
A |
11:20 |
42.8 |
43 |
42.3 |
0 |
10.1 |
0 |
SHW |
Start (Time 0) |
B |
11:20 |
41.9 |
41.6 |
||||
SHW |
Dark |
A |
12:00 |
44.2 |
43.6 |
44 |
-0.039 |
10.5 |
-4 |
SHW |
Dark |
B |
12:00 |
44.5 |
43.5 |
||||
SHW |
Light |
A |
12:00 |
15.2 |
14.7 |
14.2 |
1.092 |
3.4 |
66 |
SHW |
Light |
B |
12:00 |
14.2 |
12.8 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The calculated overall half-life (in synthetic humic water) is less than 1 hour, the test substance is considered “photolabile” and the definitive study is not applicable.
- Executive summary:
Tests were conducted to determine whether natural humic acid significantly enhances the aqueous photolysis of the test substance. During the preliminary screening test, quartz tubes containing the test substance in distilled water and synthetic humic water at pH 7 were exposed to summer sunlight. The concentration of the test substance was monitored at time zero and 40 minutes using high performance liquid chromatography (HPLC). No significant losses were observed in the dark controls, and the loss of the test substance in sunlight was 1.6 times faster in synthetic humic water than in distilled water. Because the calculated overall half-life (in synthetic humic water) is less than 1 hour, the test substance is considered “photolabile” and the definitive study is not applicable. The results yielded the following kinetic data corresponding to photolysis at 40°C in summer at the surface of a flat water body with an absorbance of 0.1 at 290 nm: - Direct photolysis rate constant: 3.7 d-1 - Indirect photolysis rate constant: 2.2 d-1 - Overall photolysis rate constant: 5.9 d-1 - Overall photolysis half-life: 0.12 d (56 min). The test substance is very photolabile, and both direct and indirect photolysis contribute significantly to its phototransformation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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