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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Very limited information on methodology and results reported. Non-standard method for acute toxicity testing.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1977

Materials and methods

Principles of method if other than guideline:
The LD50 of the test substance given to rats via i.p. is reported.
GLP compliance:
no

Test material

Constituent 1
Details on test material:
- Purity: Not reported

Test animals

Species:
rat
Strain:
other: Charles River CD
Sex:
male/female

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
other: 10% DMSO
No. of animals per sex per dose:
5 per group

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
37 mg/kg bw
95% CL:
30 - 47

Applicant's summary and conclusion

Executive summary:

The LD50 of the test substance in 10% DMSO given to rats via i.p. is 37 mg/kg.