Registration Dossier
Registration Dossier
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EC number: 203-404-7 | CAS number: 106-50-3
Endpoint summary
Administrative data
Description of key information
Skin: No skin irritation was observed in guinea pigs at concentrations of 30 and 3%
Eye (equivalent to OECD 405): Moderate ocular effects observed in rabbits
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
No skin irritation was observed in guinea pigs after 24- or 48-hour exposure to concentrations of 30% and 3%. The test substance produced moderate ocular effects, including generalized slight corneal cloudiness, moderate iritis, and moderate conjunctivitis in an unwashed eye; and generalized slight corneal cloudiness, moderate iritis, and mild conjunctivitis in an eye washed after application
Effects on eye irritation: irritating
Justification for classification or non-classification
The test substance did not produce skin irritation, but produced moderate ocular effects in rabbits. The substance should be classified as Xi; R36: Irritating to eyes according the EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
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