Registration Dossier
Registration Dossier
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EC number: 500-094-8 | CAS number: 37208-53-0 1 - 6.5 moles propoxylated
Endpoint summary
Administrative data
Description of key information
LD50 (oral) > 2500 mg/kg bw (2000 mg/kg tested, no effects observed).
LD50 (dermal) > 2000 mg/kg bw.
Key value for chemical safety assessment
Additional information
In an acute oral toxicity study according to OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method), 6 female Sprague-Dawley rats were exposed to 2000 mg/kg bw. No clinical signs were observed. Although the highest dose tested were 2000 mg/kg bw the study director concluded the LD50 to be >2500 mg/kg as no deaths occurred (ISOPA Brussels, 2002a).
In an acute dermal toxicity study according to OECD Guideline 402 (Acute Dermal Toxicity), 5 male and 5 female Sprague-Dawley rats were exposed to 2000 mg/kg bw. No clinical signs were observed, resulting in a LD50 > 2000 mg/kg bw (ISOPA Brussels, 2002b).
Justification for classification or non-classification
Findings from acute toxicity testing do not warrant classification.
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