Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-798-3 | CAS number: 126-71-6
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- Activated sludge from laboratory wastewater plant treating municipal sewage.
Concentration of activated sludge in the test assay: 30 mg/L dry substance - Duration of test (contact time):
- 28 d
- Initial conc.:
- 37 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 70 - 80
- Sampling time:
- 28 d
- Details on results:
- - Duration of adaptation phase: 8 days
- Duration of degradation phase: 20 days
- Degradation degree of DOC at the end of the test, mean value: 90-100 % - Results with reference substance:
- - Degradation degree of the reference substance after 14 days: 80-90 %
- Degradation degree in the inhibition control after 14 days: 70-80 % - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
Reference
Description of key information
Readily biodegradable: 79-82% in 28 days (OECD 301B)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Two studies investigating the ready biodegradability of Triisobutyl phosphate (TiBP) are available. The key study was conducted according to GLP and OECD guideline 301B using non-adapted activated sludge from a domestic STP as inoculum (BASF 2019). After 28 days 79-82% degradation of TiBP was observed and the 10d-window was passed. Thus, the substance was classified as readily biodegradable. This was confirmed by a second study also conducted to GLP and OECD guideline 301B, which just missed to fulfill the 10d-window criterion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
