Registration Dossier
Registration Dossier
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EC number: 204-798-3 | CAS number: 126-71-6
Repeated dose toxicity: other routes
Administrative data
- Endpoint:
- repeated dose toxicity: other route
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 953
- Report date:
- 1953
- Reference Type:
- secondary source
- Title:
- Unnamed
- Report date:
- 1953
Materials and methods
- Principles of method if other than guideline:
- BASF-Test
- GLP compliance:
- no
Test material
- Reference substance name:
- Triisobutyl phosphate
- EC Number:
- 204-798-3
- EC Name:
- Triisobutyl phosphate
- Cas Number:
- 126-71-6
- Molecular formula:
- C12H27O4P
- IUPAC Name:
- triisobutyl phosphate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male/female
Administration / exposure
- Route of administration:
- other: Pfefferminztee (in der Traenke)
- Duration of treatment / exposure:
- 51 Tage
- Frequency of treatment:
- taeglich
Doses / concentrations
- Dose / conc.:
- 6 316 ppm
- Remarks:
- according to 430-440 mg/kg/day; m-w
- Control animals:
- yes, concurrent vehicle
- Details on study design:
- Post-exposure period: keine Angabe
Results and discussion
Results of examinations
- Details on results:
- Kein Einfluss auf die Koerpergewichtsentwicklung, vermehrtes Auftreten von "Nierenreizungen" im Vergleich zur Kontrollgruppe (wird von den Autoren als belanglos bezeichnet).
Effect levels
- Dose descriptor:
- NOAEL
- Remarks on result:
- other: not determined
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
