Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 305-998-4 | CAS number: 95465-85-3
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Two reliable chronic toxicity studies were identified. the first study by Biesinger and Christensen reported a 21d-EC16 of 5.8 mg Ba/L (nominal values), which can be used for the estimation of a NOEC-value of 2.9 mg/L (i.e., EC16/2; ECHA-guidance).
The second data point was generated for the marine invertebrate Cancer anthonyi (Macdpnald et al, 1988). Here, a nominal, 7d-NOEC of 10 mg Ba/L was reported, and this for the endpoint embryonal hatching.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.9 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 10 mg/L
Additional information
According to ECHA Guidance, a NOEC can be estimated by dividing a reliable ECX by 2, and this when x is situated between 10 and 20 % effect. The 21d-EC16 of 5.8 mg Ba/L for D. magna, as reported by Biesinger and Christensen (1972) is in compliance with this criterion. Therefore a NOEC of 2.9 mg Ba/L could be derived for the freshwater compartment.
For C. anthonyi, 24h-acclimated embryo's stripped from the pleopods of ovigerous females were used as test organisms. This type of life-stage is generally considered as the most sensitive one, and a 7 day exposure period combined with the endpoint under consideration (i.e., hatching/development) should therefore result in relevant chronic effects data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
