Registration Dossier
Registration Dossier
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EC number: 202-476-7 | CAS number: 96-09-3
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: no information available whether the calculation model is validated for the substance under investigation
Data source
Reference
- Reference Type:
- other: unpublished calculation
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The bioconcentration factor of styrene oxide was calculated using EPIWIN v3.20, BCFWIN v2.17.
- GLP compliance:
- no
Test material
- Reference substance name:
- (epoxyethyl)benzene
- EC Number:
- 202-476-7
- EC Name:
- (epoxyethyl)benzene
- Cas Number:
- 96-09-3
- Molecular formula:
- C8H8O
- IUPAC Name:
- 2-phenyloxirane
Constituent 1
Test conditions
- Details on estimation of bioconcentration:
- BASIS FOR CALCULATION OF BCF
- Estimation software: EPIWIN v3.20, BCFWIN v2.17
- Result based on measured log Pow of: 1.61
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- 3.5
Any other information on results incl. tables
The bioconcentration factor of styrene oxide was calculated using EPIWIN v3.20, BCFWIN v2.17. The calculation yielded a BCF=3.5 taking into account the measured log Kow=1.61. The result indicates a very low potential for bioaccumulation. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the result and the conclusion thereof should be treated with care.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The bioconcentration factor of styrene oxide was calculated using EPIWIN v3.20, BCFWIN v2.17. The calculation yielded a BCF=3.5 taking into account the measured log Kow=1.61. The result indicates a very low potential for bioaccumulation. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the result and the conclusion thereof should be treated with care.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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