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Toxicological information

Toxicity to reproduction

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Administrative data

Endpoint:
toxicity to reproduction
Remarks:
other: subchronic inhalation toxicity study
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 413 guideline study
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Propan-1-ol
EC Number:
200-746-9
EC Name:
Propan-1-ol
Cas Number:
71-23-8
Molecular formula:
C3H8O
IUPAC Name:
propan-1-ol

Test animals

Species:
rat
Strain:
Wistar

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Remarks on result:
other: see IUC6 section 7.5.2, endpoint record "Key.OECD413"

Results: F1 generation

Effect levels (F1)

Remarks on result:
other: see IUC6 section 7.5.2, endpoint record "Key.OECD413"

Overall reproductive toxicity

Reproductive effects observed:
not specified

Any other information on results incl. tables

see IUC6 section 7.5.2, endpoint record "Key.OECD413"

Applicant's summary and conclusion