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Toxicological information

Basic toxicokinetics

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Administrative data

Endpoint:
basic toxicokinetics, other
Remarks:
Assessment, based on physico-chemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The assessment of the toxicokinetik of 3 -isocyanatomethyl-3,5,5-trimethyl-cyclohexyl isocyanate homopolymer (IPDI homopolymer) is based on physico-chemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.

Data source

Reference
Reference Type:
other: Toxicokinetic Assessment
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Principles of method if other than guideline:
Assessment on toxicokinetics

Test material

Constituent 1
Chemical structure
Reference substance name:
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers
EC Number:
500-125-5
EC Name:
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers
Cas Number:
53880-05-0
Molecular formula:
residual C12H18N2O2, otherwise C36H54N6O6 (trimer) and higher species
IUPAC Name:
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer
Constituent 2
Chemical structure
Reference substance name:
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type
EC Number:
931-312-3
Cas Number:
53880-05-0
Molecular formula:
residual C12H18N2O2, otherwise C36H54N6O6 (trimer) and higher species
IUPAC Name:
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type

Results and discussion

Any other information on results incl. tables

The remarks on the toxicokinetics of 3 -isocyanatomethyl-3,5,5-trimethyl-cyclohexyl isocyanate homopolymer (IPDI homopolymer) are based on physico-chemical properties of the compound and on toxicological data. Experimental toxicokinetic studies were not performed.

Applicant's summary and conclusion