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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Experimental data of test chemicals
Justification for type of information:
Experimental data of test chemicals is from collection of data
Reason / purpose for cross-reference:
read-across source
Reason / purpose for cross-reference:
read-across source
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
WoE report is based on two short term toxicity study of fish for the test chemical :
1.To study the effects of test material, toxicity to aquatic algae and cyanobacteria test was carried out for 72 hr.
2.To evaluate toxicity of test material on Chlorococcales
GLP compliance:
no
Analytical monitoring:
not specified
Test organisms (species):
other: 1.Desmodesmus subspicatus , 2.Chlorococcum sp.
Details on test organisms:
1.common name: Green Algae
age: Exponential growth phase (log)
COMMENT: 10000 CELLS/ML
Test type:
static
Water media type:
freshwater
Total exposure duration:
72 h
Test temperature:
23 deg C
Details on test conditions:
3 REPLICATES, MINERAL SALT TEST MEDIUM
Reference substance (positive control):
not specified
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
6.61 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: 95% conf. limit : 5.78 - 7.63 mg/L
Remarks:
Read across 1
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
230 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
biomass
Remarks on result:
other: Read across 2
Validity criteria fulfilled:
not specified
Conclusions:
The test chemical is likely to be not toxic to aquatic algae and cyanobacteria in the dose range of 230 mg/l.
Executive summary:

Data available for the test chemical has been reviewed to determine the toxicity of aquatic algae and cyanobacteria of the test chemical .The studies are as mentioned below:

To study the effects of test material, ethoxylated toxicity to aquatic algae and cyanobacteria test was carried out for 72 hr.Effective concentration EC50 to 50% of Desmodesmus subspicatus when expeosed to test material for 72 hr is 6.61 mg/L.

First study was supported by the second. Test material was used to evaluate its toxicity on Chlorococcales green algae for 24 hrs in static condition . The effect concentration (EC50) at which population of algae was effect was observed to be 230 mg/l.The test chemical is not likely to be toxic to aquatic algae and cyanobacteria  in the dose range of 23 mg/l.

Based on the above effect concentrations it can be concluded that test material is toxic to aquatic algae and can be classified as aquatic chronic 3 as per CLP criteria.

Description of key information

The test chemical  is  likely to be not toxic to aquatic algae and cyanobacteria  in the dose range of 230 mg/l.

Key value for chemical safety assessment

EC50 for freshwater algae:
6.61 mg/L

Additional information

Toxicity to aquatic algae and cyanobacteria:

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the toxicity of aquatic algae and cyanobacteria of the test chemical .The studies are as mentioned below:

To study the effects of test material, ethoxylated toxicity to aquatic algae and cyanobacteria test was carried out for 72 hr.Effective concentration EC50 to 50% of Desmodesmus subspicatus when expeosed to test material for 72 hr is 6.61 mg/L.

First study was supported by the second. Test material was used to evaluate its toxicity on Chlorococcales green algae for 24 hrs in static condition . The effect concentration (EC50) at which population of algae was effect was observed to be 230 mg/l.The test chemical is not likely to be toxic to aquatic algae and cyanobacteria  in the dose range of 23 mg/l.

Based on the above effect concentrations it can be concluded that test material is toxic to aquatic algae and can be classified as aquatic chronic 3 as per CLP criteria.