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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Microorganism toxicity was assessed in a reliable activated sludge respiration inhibition study performed according to the new version of the OECD 209 guideline and compliant to GLP. 

Key value for chemical safety assessment

EC50 for microorganisms:
335 mg/L
EC10 or NOEC for microorganisms:
12 mg/L

Additional information

A new reliable (reliability category 1) study for the submission substance was performed according to OECD 209 (adopted 2010) and compliant to GLP. The mean inhibition of the respiration rates for the tested concentrations was 8.8% at 10 mg/L, 21% at 32 mg/L, 31% at 100 mg/L, 48% at 320 mg/L and 68% at 1000 mg/L compared to the control, i.e. a clear concentration-effect relationship on the inhibition of the respiration rate was determined.

Based on these results, the ECX values and their 95% confidence limits were calculated as follows:

EC10 12 mg/L, 95% confidence limits: 6.4 - 18 mg/L

EC20: 37 mg/L, 95% confidence limits: 25 - 51 mg/L

EC50: 335 mg/L, 95% confidence limits: 267 - 432 mg/L

EC80: >1000 mg/L