Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-177-4 | CAS number: 7440-69-9
Endpoint summary
Administrative data
Description of key information
Bismuth metal is not acutely toxic via oral, dermal or inhalation route.
Key value for chemical safety assessment
Additional information
In an acute oral toxicity test in rats with bismuth (mean particle diameter was 10 µm), no deaths occurred at a dose of 2000 mg/kg body weight. Therefore the LD50 is >2000 mg/kg bw for both sexes.
An acute dermal toxicity study with bismuth metal is considered to be scientifically unjustified.
An acute inhalation study with bismuth metal powder is considered to be technically not feasible, since it was not possible to generate a stable aerosol atmosphere with a mass median aerodynamic diameter (MMAD) of < 4 µm.
Justification for classification or non-classification
In an acute oral toxicity test in rats with bismuth, the LD50 was determined to be >2000 mg/kg bw.
An acute dermal toxicity study with bismuth metal is considered to be scientifically unjustified.
An acute inhalation study with bismuth metal powder is considered to be technically not feasible.
The available information indicates that bismuth metal is not acutely toxic or harmful. Therefore, classification of bismuth metal for acute toxicity is not warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
