Registration Dossier
Registration Dossier
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EC number: 231-944-3 | CAS number: 7779-90-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Used in EU risk assessment for zinc phosphate
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Trizinc bis(orthophosphate)
- EC Number:
- 231-944-3
- EC Name:
- Trizinc bis(orthophosphate)
- Cas Number:
- 7779-90-0
- Molecular formula:
- H3O4P.3/2Zn
- IUPAC Name:
- trizinc bis(orthophosphate)
- Details on test material:
- Zinc phosphate is the test material
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No data
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- No data
- Doses:
- Not specified
- No. of animals per sex per dose:
- No data
- Control animals:
- not specified
- Details on study design:
- No data
- Statistics:
- No data
Results and discussion
- Preliminary study:
- Not applicable
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Mortality:
- no mortality
- Clinical signs:
- other: no effects
- Gross pathology:
- no effects
- Other findings:
- None
Any other information on results incl. tables
None
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- LD50 oral rat is >5000 mg zinc phosphate/kg bw
- Executive summary:
Zinc phosphate was tested in an oral limit test according to OECD guidelines using Wistar rats. No mortality occurred and no signs of toxicity was observed. The LD50 is >5000 mg zinc phosphate/kg bw.
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