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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary citation in handbook, original reference not available

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Patty's industrial hygiene and toxicology: 2.5.4 Dicumyl peroxide
Author:
Calyton GD, Clayton FE
Year:
1993
Bibliographic source:
572-573, Wiley-Interscience, John Wiley & Sons, New York, NY
Reference Type:
secondary source
Title:
Unnamed
Year:
1970

Materials and methods

Principles of method if other than guideline:
Secondary source, no information on method
GLP compliance:
not specified
Test type:
other: limit test
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis(α,α-dimethylbenzyl) peroxide
EC Number:
201-279-3
EC Name:
Bis(α,α-dimethylbenzyl) peroxide
Cas Number:
80-43-3
Molecular formula:
C18H22O2
IUPAC Name:
1,1'-(dioxydipropane-2,2-diyl)dibenzene

Test animals

Species:
other: rats, guinea pigs, mice
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
not specified
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
4 h
Concentrations:
0.1 mg/L (= 100 mg/m3)
No. of animals per sex per dose:
2 animals of each species tested
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
> 0.1 mg/L air (nominal)
Based on:
not specified
Remarks on result:
other: No further information reported in secondary source

Applicant's summary and conclusion