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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Ethylenediamine, propoxylated was negative in three assays:

- bacterial reverse mutation assay

- in vitro HPRT cell mutation assay (OECD 476)

- in vitro micronucleus test (OECD 487)

In addition, the results for one further assay from Ethylenediamine, ethoxylated and propoxylated, was also negative.

- Negative result read across from an in-vitro chromosome aberration test with Chinese Hamster V79 cells

Short description of key information:
Three in vitro mutagenicity tests using different end points were all negative. Therefore further testing is not required.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The results from in-vitro testing of genetic toxicity do not warrant classification according to EU GHS.