Registration Dossier
Registration Dossier
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EC number: 287-827-2 | CAS number: 85586-24-9
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish.
Key value for chemical safety assessment
Additional information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no further long-term toxicity test to fish is proposed.
The available experimental studies used for the assessment of aquatic toxicity offatty acids, C8-10, tetraesters with pentaerythritol (CAS 85586-24-9), no acute toxic effects were observed up to the limit of water solubility. Furthermore, the long term test on the reproduction of daphnids also does not reveal any adverse effects.Asthere was no sign that fish are the most sensitive species in the short term tests, it cannot be expected that a long-term test with fish will generate different results than the existing long-term test with invertebrates.Hence due to animal welfare reasons and to avoid unnecessary vertebrate tests, no further long-term test with fish is required forfatty acids, C8-10, tetraesters with pentaerythritol (CAS 85586-24-9).
In addition,due toits ready biodegradability it is not likely that aquatic organisms are exposed to the test substance since it will be ultimately degraded in sewage treatment plants.
Therefore, it can be concluded that chronic exposurefatty acids, C8-10, tetraesters with pentaerythritol (CAS 85586-24-9)to fish is unlikely and that it would not pose a higher risk to fish than it does to daphnids.
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