Registration Dossier

Environmental fate & pathways

Hydrolysis

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Description of key information

The registered substance exhibits an estimated half-life of 139 d for pH 7 at 25°C (calculated from experimental data at 50, 65 and 80°C) and has to be considered as stable to hydrolysis

Key value for chemical safety assessment

Half-life for hydrolysis:
139 d
at the temperature of:
25 °C

Additional information

The test material was insoluble in water (far from 100 mg/L). Thus, test material meets the definition of poorly water soluble substances and has to be considered as a "difficult substance to test" according to OECD Guidance No 23 (2000) on aquatic toxicity testing of difficult substances and mixtures. A hydrolysis study has been performed according to OECD TG 111. The results of Tier 1 (50°C) indicated that HDI Trimer MEKO-blocked was unstable to hydrolysis. Tier 2 testing was performed at three pH and three temperatures (higher ones for pH 7 and 9). HDI Trimer MEKO-blocked exhibits an estimated half-life of 139 d for pH 7 at 25 °C (calculated from experimental data at 50, 65 and 80 °C).