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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Justification for the non-equivalence of the test material to the submission substance identity:

HDI trimer MEKO blocked is always produced and marketed as dissolved in solvent. Thus, the substance is reasonably expected to be handled and used in a form of a mixture of the registered substance in the solvent. The environment is anticipated to be exposed rather to the mixture than to the pure substance. Thus, the testing strategy was designed to take this route of exposure into account and

it has been concluded that testing the mixture was more relevant than testing the registered substance as such.

To conclude, ecotoxicological studies were performed on the mixture and as a consequence for endpoint study records, the test material is ticked as ‘no’ when requesting if equivalent to submission substance identity.

Available ecotoxicological information:

Four study reports record experimental results on ecotoxicological properties of the registered substance in the solvent. Among them, three references deal with aquatic organisms, the other one with microorganisms. An overview of the ecotoxicological dataset is provided in the table below.




Basis for effect


Effect concentration (mg/L)


Short-term toxicity to fish

Similar to OECD 203

Danio rerio



141.4 (nom.)

Bayer, 1988

Short-term toxicity to aquatic invertebrates

OECD 202

Daphnia magna



> 1.61 (meas. Initial)

Weyers, 2007

Toxicity to aquatic algae

OECD 201

Desmodesmus subspicatus

Growth rate and biomass


> 8.1 (nom.)

Weyers, 2007

Toxicity to microorganisms

OECD 209

Not identified



> 10000 (nom.)

Bayer, 1988


Based on the available results, the registered substance does not exhibit acute toxicity effects at its solubility limit to the three trophic levels and the microorganisms.