Registration Dossier

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
other: Toxicokinetics assessment
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Based on the known physico-chemical properties and the available toxicologic studies, a justified assessment of the toxicokinetic and biotransformational properties of HDI Trimer MEKO-blocked could be made, therefore an in vivo toxicokinetic study is at present not an urgent requirement.

Data source

Reference
Reference Type:
other: Toxicocinetics assessment
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Principles of method if other than guideline:
Assessment of Toxicokinetics

Test material

Constituent 1
Reference substance name:
85940-94-9
Cas Number:
85940-94-9
IUPAC Name:
85940-94-9

Results and discussion

Any other information on results incl. tables

Based on the known physico-chemical properties and the available toxicologic studies, a justified assessment of the toxicokinetic and biotransformational properties of HDI Trimer MEKO-blocked could be made, therefore an in vivo toxicokinetic study is at present not an urgent requirement.

Applicant's summary and conclusion