Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 252-104-2 | CAS number: 34590-94-8
Endpoint summary
Administrative data
Description of key information
Additional information
Acute toxicity studies have been conducted in fish, daphnia and algae. In summary, for the aquatic compartment dipropylene glycol methyl ether shows EC50s/LC50s that exceed 1000 mg/l in daphnia (48 hr), fish (96 hr) and algae (7 days). The NOEC for reproduction of Daphnia magna corresponds to the highest concentration tested of 0.5 mg/L in the long-term test, which was set very low considering the low acute toxicity of the substance on Daphnia magna. The low chronic toxicity is highlighted in a freshwater algae test with a NOEC at 1000 mg/L. An activated sludge respiration inhibition test showed an EC50 of 4168 mg/l for micro-organisms. Dipropylene glycol methyl ether is readily biodegradable and has very low potential for bioaccumulation (log Kow <1). According to REACH Annex IX requirements, long-term toxicity testing shall only be considered when the chemical safety assessment indicates the need for further investigations. Hence, long-term testing in aquatic species (fish) can be waived for dipropylene glycol methyl ether.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
