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Registration Dossier
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EC number: 211-708-6 | CAS number: 688-84-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
In water 2-ethylhexyl methacrylate (2-EHMA) will be rapidly biodegraded, abiotic degradation by hydrolysis is not of major concern. From the water surface the test substance has a high volatility. After exposure to air it will be rapidly degraded by photochemical processes (half life 13.3 h). Based on a logPow of 4.95, 2-EHMA would be expected to have a significant bioaccumulation potential. In an actual bioaccumulation test with fish, however, only a bioaccumulation rate of 37 was observed, most likely due to rapid metabolism. Soil adsorption/desorption studies have been performed with MAA, MMA and iBMA. Koc values for EMA, n-Butyl methacrylate (nBMA) and 2-Ethylhexyl methacrylate (2 –EHMA) were estimated by regression from the measured data (Staples, 2009).
Adsorption of the structural related substance isobutyl methacrylate ( iBMA) to soil was measured in three types of soil and the Koc ranged from 1480 to 3920 with a mean of 2760. It should be recognised that when interpreting the measured data of Christensen that they had assumed binding to soil since they could not detect iBMA in the aqueous desorption phase. However, failed to use sterilised soil and therefore rapid biodegradationby soil microflora may have contributed to the disappearance of iBMA from the aqueous phase and the true Koc is likely to be lower than that assumed. On this basis the estimates made by Staples for 2-EHMA with a value of 6400 may also be too high.
A low bioaccumulation potential of 2-EHMA was demonstrated in a bioaccumulation study in fish (cf above).
Furthermore, based on a Mackay Level 1 calculation the substance will mainly partition to air (ca. 90.7 %) in this equilibrium model, and to a much lesser degree to soil (4.5 %) and sediment (4.2 %). In the Mackay Level III model, which additionally takes into account transport and degradation processes 2-EHMA, when released to air or water, will predominantly remain in the environmental compartment into which it was released (air: 98.6 %; water: 95.5 %). REACH annex VIII (9.3.1) states that an adsorption/desorption study does not need to be conducted if:
— based on the physicochemical properties the substance can be expected to have a low potential for adsorption (e.g. the substance has a low octanol water partition coefficient), or
— the substance and its relevant degradation products decompose rapidly.
Hence, testing is not required.
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