Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-603-9 | CAS number: 108-65-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A non GLP-study according to OECD guideline 202 and a GLP study equivalent to OECD guideline 202 are available as key studies for propylene glycol methyl ether acetate. These studies are supported by a GLP-study (full report not available) and a non-GLP study equivalent or similar to OECD guideline 202.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 408 mg/L
Additional information
In an acute test under semi-static conditions a concentration of 500 mg/l of propylene glycol methyl ether acetate was used. Based on this nominal concentration, the 48-hour EC50 was determined to be superior to 500 mg/l as no immobility was observed. Another acute study in Daphnia magna was carried out under static conditions exposing Daphnia to concentrations ranging from 70 to 2,500 mg/l propylene glycol methyl acetate. Based on these nominal concentrations, the 48-hour LC50 was determined to be 408 mg/l. Supporting studies carried out under static conditions used concentrations ranging from 5 to 1,000 mg/l of propylene glycol methyl ether acetate. Based on these nominal concentrations, 48-hour EC50s of 380 mg/l and 373 mg/l were determined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
