Registration Dossier
Registration Dossier
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EC number: 203-603-9 | CAS number: 108-65-6
Endpoint summary
Administrative data
Description of key information
Additional information
No terrestrial toxicity studies are available for propylene glycol methyl ether acetate. The risk characterisation shows that the PEC/PNEC ratio for soil is clearly < 1, indicating no need for further information and testing. Propylene glycol methyl ether acetate is highly water soluble (completely miscible) and has a very low potential for adsorption to organic matter. Therefore, the predicted no effect concentration (PNEC) for soil was derived from the PNEC for freshwater using the equilibrium partitioning method. This method is applicable for substances where the toxicity in soils relates to the freely dissolved concentration in pore water. The distribution modelling (Mackay level III fugacity modeling) indicates that when propylene glycol methyl ether acetate is released to air, the substance will react with hydroxyl radicals. If released directly to water, most of the substance will remain in the water compartment and is expected to be biodegraded. If released to soil, the substance is expected to be biodegraded. Hence testing of effects on terrestrial organisms can be waived for propylene glycol methyl ether acetate.
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