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Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2007
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer
Principles of method if other than guideline:
Determination of octanol solubility.
The analytical method for the determination is in agreement with the method that was agreed upon at the Analytical Experts Meeting of ETAD (Basel) on January 12, 2005.
Medium:
n-octanol
Solubility:
8.63 mg/L
Temp.:
23 °C
Remarks on result:
other: The determination of octanol solubility was conducted at ambient temperature (23-24 °C).
Details on results:
The value above represents the mean from 3 determinations (sigma=0.14). See below for indidividual results.

Individual results:

 

Absorption
(d = 10 cm)

mg/L

a1

0.4987

8.54

a2

0.4997

8.56

a3

0.5133

8.79


Conclusions:
The test substance has an octanol solubility of 8.63 mg/L.
Executive summary:

The octanol solubility was determined by UV-Vis analysis of the dissolved test substance amount in 30 mL octanol according to the method that was agreed upon at the Analytical Experts Meeting of ETAD (Basel) on January 12, 2005. The test substance has an octanol solubility of 8.63 mg/L (23 -24 °C).

Description of key information

The octanol solubility was determined by UV-Vis analysis of the dissolved test substance amount in 30 mL octanol according to the method that was agreed upon at the Analytical Experts Meeting of ETAD (Basel) on January 12, 2005. The test substance has an octanol solubility of 8.63 mg/L (23 -24 °C).

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
8.63 mg/L

Additional information

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