Registration Dossier
Registration Dossier
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EC number: 233-113-0 | CAS number: 10035-10-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Thiebaud, H. (1998) reported an EC50 (48h) Daphnia = 39 mg/L. In an acute toxicity test (inhibition of mobility), Daphnia magna were exposed to concentrations of hydrobromic acid ranging from 2.09 to 47.99 mg/L, forming a geometric progression with a factor of 1.7. Test concentrations were measured by ionic chromotography, and EC50 values were calculated for the 24 and 48 hour periods using measured initial concentrations and regression analysis using the Probit/log model. EC50-24 hours was calculated to be 39 mg/L hydrobromic acid with 95 % confidence interval ranging from 26 to 100 mg/L. The EC50-48 hours was calculated to be 19 mg/L with 95 % confidence interval ranging from 15 to 25 mg/L.
Though there are minimal data on hydrogen bromide (HBr) available there are sufficient data available on the analogue substances hydrogen chloride (HCl) and phosphorus tribromide which hydrolyses to phosphonic acid and HBr. (Read-across justifications in Section 8.6 Repeat dose toxicity.)
Mattie, D.R., et al. (1996b) reported an LC50 (48h) = 22.6 mg/L on the analogue substance PBr3.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 19 mg/L
Additional information
Thiebaud, H. (1998) reported an EC50(48h) Daphnia= 39 mg/L. In an acute toxicity test (inhibition of mobility),Daphnia magna were exposed to concentrations of hydrobromic acid ranging from 2.09 to 47.99 mg/L, forming a geometric progression with a factor of 1.7. Test concentrations were measured by ionic chromotography, and EC50 values were calculated for the 24- and 48-hour periods using measured initial concentrations and regression analysis using the Probit/log model. EC50-24 hours was calculated to be 39 mg/L hydrobromic acid with 95 % confidence interval ranging from 26 to 100 mg/L. The EC50-48 hours was calculated to be 19 mg/L with 95 % confidence interval ranging from 15 to 25 mg/L.
Though there are minimal data on hydrogen bromide (HBr) available there are sufficient data available on the analogue substances hydrogen chloride (HCl) and phosphorus tribromide which hydrolyses to phosphonic acid and HBr. (Read-across justifications in Section 8.6 Repeat dose toxicity.)
Mattie, D.R., et al. (1996b) reported an LC50(48h) = 22.6 mg/L on the analogue substance PBr3.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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