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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

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Description of key information

Read across to structural analogue Edetic acid. For justification of read across see section 13 of this dossier.

The dissociation constant was estimated from the measured acidity constant (at 20 °C). A range of -0.12 to 10.44 was estimated for H4EDTA with different electrolytes, ion strength and electrodes:

pKa1: 8.85 to 10.44,

pKa2: 6.07 to 6.28,

pKa3: 2.3 to 2.7,

pK4: 2 to 2.2,

pK5: 1.4,

pK6: -0.12.

Key value for chemical safety assessment

Additional information