Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 205-358-3 | CAS number: 139-33-3
Endpoint summary
Administrative data
Description of key information
Additional information
Numerous publications on observations in humans are available from the open literature. The results for skin sensitisation may only suggest irritation rather than contact allergy. No reports on occupational contact allergic reactions are available. This conclusion is supported by the independent evaluation of the MAK Commission for the Investigation of Health Hazards of Chemical Compounds in the work area (MAK, 46. Lieferung, 2009).
Dermal absorption was investigated for human volunteers indicating only 0.001 % absorption for CaNa2EDTA. It is concluded that systemic exposure via dermal route is negligible. This conclusion is supported by the independent evaluation of the MAK Commission for the Investigation of Health Hazards of Chemical Compounds in the work area (MAK, 46. Lieferung, 2009).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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