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A randomized placebo controlled triple blind study is reported to determine the health impact of daily use of sodium dichloroisocyanurate (NaDCC) tablets for household drinking water. NaDCC use did not prevent diarrhea but improved water quality. 

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A randomized placebo controlled triple blind study is reported to determine the health impact of daily use of sodium dichloroisocyanurate (NaDCC) tablets for household drinking water treatment in periurban Ghana (Jain et al 2010).

240 households were randomized (3, 240 individuals) to receive either NaDCC or placebo tablets. All households received a 20 -L safe water storage vessel. Over 12 weeks, 446 diarrhea episodes (2.2%) occurred in intervention and 404 (2.0%) in control households (P = 0.38). Residual free chlorine levels indicated appropriate tablet use. E. coli was found in stored water at baseline in 96% of intervention and 88% of control households and at final evaluation in 8% of intervention and 54% of control households (P = 0.002). NaDCC use did not prevent diarrhea but improved water quality. Diarrhea rates were low and water quality improved in both groups. A follow up health impact study of NaDCC tablets is warranted.