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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Description of key information

No in vivo data are available concerning carcinogenic effects of the test substance.


Based on the data described in chapter 7.6 the substance shows no genotoxic effects and there is no evidence from the repeated dose study that the substance is able to induce pre-neoplastic lesions. According to Annex X (column 2 of section 8.9.1) and according to Annex X (preface) a carcinogenicity study is not required.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Additional information

No in vivo carcinogenicity data are available for the test substance. An in vitro cell transformation test (Huntsman-1982, validity 2) was


conducted with balb/3T3 mouse cells, similarly to the EU Method B.21 (In Vitro Mammalian Cell Transformation Test). The test


concentrations were 4.38, 17.5, 35, 70, 105 nL/mL. No indication of cell transformation could be evidenced at


all tested concentrations. Thus, the test substance was negative in the cell transformation test with balb/3T3 mouse cells.