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Dissociation constant

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Description of key information

The study is technically not feasible.

Key value for chemical safety assessment

Additional information

According to ECHA's "Guidance on information requirements and chemical safety assessment, Chapter R.7a: Endpoint specific guidance", the study on determining the dissociation constant does not need to be conducted for the following reasons:

1)  the analytical method is not sensitive enough in order to determine a dissociation constant in aqueous phase since the water solubility is very low.

2) The substance does not contain any functional groups which are considered relevant for dissociation.

The endpoint therefore is suggested to be waived.