Registration Dossier
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EC number: 274-581-6 | CAS number: 70356-09-1
Endpoint summary
Administrative data
Description of key information
Additional information
Stability:
Study on hydrolysis waived due to the extremely poor water solubility of the test item of 0.027 mg/L.
Biodegradation:
Both a study on anaerobic biodegradability and a study on (aerobic) inherent biodegradability revealed that the substance is not biodegradable. Based on ECHA Guidance "R.11 PBT Assessment", if the test item is not degradable in an inherent biodegradability study, the substance shall be considered as non biodegradable and further testing shall not be considered. The substance therefore is assessed to be persistent.
Bioaccumulation:
It is concluded from experimental results obtained from a fish dietary bioaccumulation study with rainbow trout that BMDBM is taken up by rainbow trout up to a certain extent resulting to a lipid normalized BMF which is far below 1 (BMF Lipid = 0.1218). BMDBM was eliminated from rainbow trout with a half-life of 3.83 days. These results indicate that the bioaccumulation and biomagnification potential is low.
Transport and distribution:
The computational approach (QSPR) for deriving the Koc is based on the real physical properties of the test item, i.e. the experimentally derived log Kow of 6.1. When using the geometric mean of the results of four different QSPR models, the resulting log Koc is 4.65 (Koc = 44242 L/kg). Based on this result BMDBM has to be considered as "immobile" in sediments or soil.
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