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Long-term toxicity to fish

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Description of key information

As indicated in the hydrolysis study acetone cyanhydrin hydrolyses rapidly within minutes to acetone and cyanide. The study was performed over 24 hours. Therefore the toxic principle is the cyanide ion. The hydrolysis products of acetone cyanhydrin were very toxic against fish.

Key value for chemical safety assessment

Additional information

(Following quotation taken with kind permission from ECETOC JACC report no. 53; Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5):
For chronic fish toxicity studies, reliable NOEC values ranged from 1 to 29
μg CN-/l