Sodium formate

Hydrolysis

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

hydrolysis

Type of information:

other: expert statement

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

Expert judgement

GLP compliance:

no

Transformation products:

not measured

Key result

Remarks on result:

other: Sodium formate dissociates in water to sodium ion and formate ion, both of which are considered stable in water. A carboxylic acid is generally the final product of hydrolysis reactions.

Sodium formate dissociates in water to sodium ion and formate ion. Both of these are considered stable in water. 

A carboxylic acid is generally the final product of hydrolysis reactions.

Validity criteria fulfilled:

not applicable

Conclusions:

The handbook of chemical property estimation methods (Lyman et al., 1990) states that sodium formate dissociates in water to sodium ion and formate ion, both of which are considered stable in water. A carboxylic acid is generally the final product of hydrolysis reactions.

Executive summary:

An expert judgement is available based on reliable handbook data for sodium formate, which describes how sodium formate will dissociate in water to sodium and formate ions, both of which are hydrolytically stable in water (Lyman et al., 1990).

 

It is therefore concluded that no hydrolysis testing is required for sodium formate, given that the material is a salt that is known to dissociate (hydrolyze) in water upon dissolution. Testing is therefore considered impossible based on chemical principles, as the anticipated concentration of undissociated material is near zero.

Reference 2

Endpoint:

hydrolysis

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is readily biodegradable

Justification for type of information:

In accordance with column 2 of REACH Annex VII, the study does not need to be performed if the substance is readily biodegradable. Sodium formate is readily biodegradable (KM Lab, 1998).

Reason / purpose for cross-reference:

data waiving: supporting information

Description of key information

Besides being readily biodegradable, sodium formate dissociates in water to sodium ion and formate ion.

Both of these are considered stable in water. A carboxylic acid is generally the final  product of hydrolysis reactions (Lyman, 1990).

No testing is required because the material is a salt that is known to dissociate (hydrolyze) in water upon dissolution. Testing is considered impossible based on chemical principles as the anticipated concentration of undissociated material is near zero.

In accordance with column 2 of REACH Annex VII, the study does not need to be performed if the substance is readily biodegradable. Sodium formate is readily biodegradable (KM Lab, 1998).