Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Citation in a peer reviewed journal.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Unnamed
Year:
2008
Reference Type:
secondary source
Title:
IUCLID2000
Author:
EU
Year:
2000
Bibliographic source:
IUCLID2000 as it is found in ESIS.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Tada 2008 and also ESIS cited in their publications a study on the acute intraperitoneal toxicity with mice and the result of the study.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Aspartic acid
EC Number:
200-291-6
EC Name:
Aspartic acid
Cas Number:
56-84-8
Molecular formula:
C4H7NO4
IUPAC Name:
aspartic acid

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
6 000 mg/kg bw

Applicant's summary and conclusion

Conclusions:
The intraperitoneal LD50 with mice is reported to 6000 mg/kg bw.
Executive summary:

Tada 2008 and also ESIS cited in their publications a study on the acute intraperitoneal toxicity with mice and the result of the study. The intraperitoneal LD50 with mice is reported to 6000 mg/kg bw.